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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6
All Species:
52.73
Human Site:
Y48
Identified Species:
82.86
UniProt:
P62753
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62753
NP_001001.2
249
28681
Y48
L
G
E
E
W
K
G
Y
V
V
R
I
S
G
G
Chimpanzee
Pan troglodytes
XP_001147795
323
36940
Y129
L
G
E
E
W
K
G
Y
V
V
R
I
S
G
G
Rhesus Macaque
Macaca mulatta
XP_001109154
222
25518
A40
A
T
E
V
A
A
D
A
L
G
E
E
W
K
G
Dog
Lupus familis
XP_533921
249
28564
Y48
L
G
E
E
W
K
G
Y
V
V
R
I
S
G
G
Cat
Felis silvestris
Mouse
Mus musculus
NP_033122
249
28662
Y48
L
G
E
E
W
K
G
Y
V
V
R
I
S
G
G
Rat
Rattus norvegicus
P62755
249
28662
Y48
L
G
E
E
W
K
G
Y
V
V
R
I
S
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506325
213
24331
V31
G
F
P
M
K
Q
G
V
L
T
H
G
R
V
R
Chicken
Gallus gallus
P47838
249
28636
Y48
L
G
E
E
W
K
G
Y
V
V
R
I
S
G
G
Frog
Xenopus laevis
P39017
249
28658
Y48
L
G
D
E
W
K
G
Y
V
V
R
I
S
G
G
Zebra Danio
Brachydanio rerio
NP_001003728
249
28690
Y48
L
G
D
E
W
K
G
Y
V
V
R
I
S
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29327
248
28389
Y48
L
G
D
E
W
K
G
Y
Q
L
R
I
A
G
G
Honey Bee
Apis mellifera
XP_001120419
251
28877
Y48
L
G
N
E
W
K
G
Y
V
V
R
I
S
G
G
Nematode Worm
Caenorhab. elegans
Q9NEN6
246
28117
Y48
L
G
D
E
W
K
G
Y
V
V
R
I
G
G
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51430
249
28143
Y48
L
G
E
E
F
K
G
Y
V
F
K
I
M
G
G
Baker's Yeast
Sacchar. cerevisiae
P02365
236
26978
Y48
V
G
D
E
F
K
G
Y
V
F
K
I
S
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.9
88.3
98.8
N.A.
100
100
N.A.
82.3
97.9
96.3
95.5
N.A.
75
76
59.4
N.A.
Protein Similarity:
100
74.9
89.1
99.1
N.A.
100
100
N.A.
83.9
99.5
98.3
97.9
N.A.
85.9
88
76.3
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
6.6
100
93.3
93.3
N.A.
73.3
93.3
86.6
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
93.3
93.3
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
63.8
60.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
78.3
76.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
7
0
7
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
0
0
0
7
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
54
87
0
0
0
0
0
0
7
7
0
0
0
% E
% Phe:
0
7
0
0
14
0
0
0
0
14
0
0
0
0
0
% F
% Gly:
7
87
0
0
0
0
94
0
0
7
0
7
7
87
94
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
87
0
0
0
% I
% Lys:
0
0
0
0
7
87
0
0
0
0
14
0
0
7
0
% K
% Leu:
80
0
0
0
0
0
0
0
14
7
0
0
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
74
0
7
0
7
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% T
% Val:
7
0
0
7
0
0
0
7
80
67
0
0
0
7
0
% V
% Trp:
0
0
0
0
74
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
87
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _